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In this episode, we talk about grid cells and place cells. These neurons process information that relate to where an animal is located in space and are believed to be important for navigating the environment. Guests: May-Britt and Edvard Moser, Norwegian University of Science and Technology.
Participants from left to right: Edvard Moser, Jean-François Gariépy, John Kubie, Leanne Boucher and May-Britt Moser.
"0:38" Introduction
"3:14" What brought Edvard and May-Britt to neuroscience?
"8:19" Physiology and psychology.
"10:09" Behaviorism and navigation
"14:29" Navigating using maps versus visual cues
"17:58" Path integration
"23:36" Place cells - neurons that are active when an animal is located in a certain location
"32:10" Grid cells - neurons that are active at multiple spots arranged as a grid.
"48:09" The way in which grid cells encode spatial location.
http://blog.brainfacts.org/2013/11/neuro-tv-episode-5-grid-cells-and-navigation/
Many thanks to our guests! Here are some papers we talk about:
Hippocampal remapping and grid realignment in entorhinal cortex. http://www.ncbi.nlm.nih.gov/pubmed/17322902
Grid cells require excitatory drive from the hippocampus. http://www.ncbi.nlm.nih.gov/pubmed/23334581
Microstructure of a spatial map in the entorhinal cortex. http://www.ncbi.nlm.nih.gov/pubmed/15965463
The entorhinal grid map is discretized. http://www.ncbi.nlm.nih.gov/pubmed/23222610
Some Wikipedia reading:
http://en.wikipedia.org/wiki/Grid_cell
Edvard and May-Britt's homepage: http://www.ntnu.no/cbm/moser
Leanne's twitter: http://twitter.com/BoucherLeanne
John's blog: http://coronaradiata.net/
Jean-Francois' twitter: http://twitter.com/JFGariepy
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