Hydroxychloroquine, Chloroquine and Remdesivir : The COVID Cure?

   

Dr. Yo

 

Published on Mar 27, 2020

Hydroxychloroquine, Chloroquine and Remdesivir : The COVID Cure?

Hydroxychloroquine, Chloroquine, and Remdesivir are medications being used to potentially treat and cure coronavirus, aka COVID. Hydroxychloroquine (Plaquenil) and its derivative chloroquine are anti-malarial drugs that were effective in previous coronavirus outbreaks with SARS in 2002.

Remdesivir is a broadspectrum antiviral developed to treat Ebola and was found in animal studies to be effective against COVID.

Researchers are adding the antibiotic azithromycin with hydroxychloroquine to treat COVID, but this is unclear as to why.

It is believed that chloroquine works by inhibiting coronavirus, aka COVID, from invading your cells by changing the configuration of the ACE2 receptor on your cell and the spike protein on COVID. Chinese researchers showed in lab tests that hydroxychloroquine can slow infections from COVID by blocking the ACE2 receptors on your cells.

Remdesivir, developed by Gilead Sciences Inc., is an investigational broad-spectrum antiviral treatment previously tested in humans with Ebola and shown promise in animal models for treating Middle East respiratory syndrome (MERS) severe acute respiratory syndrome (SARS), which are caused by other coronaviruses.

Remdesivir doesn’t target the virus itself. Researchers have discovered that it targets the virus's system to replicate itself by mimicking the genetic code for the viral RNA, adenosine. When it comes time for your body’s polymerase enzyme to copy the viral genetic code, it starts making the wrong code because Remdesivir has tricked the enzyme into believing it is adenosine. So now, when the viral tries to use your body’s polymerase enzyme, it will make the wrong genetic code, and thus the virus cannot replicate or infect other cells.

So while there are many more medications being studied and investigated to treat COVID, hydroxychloroquine and Remdesivir are the two drugs mentioned more and more because of previous research for other infections and illnesses.
Obviously, more research needs to be done, and nothing conclusive will be available anytime soon.

- Dr. Yo

#covid #covid19

How Does Coronavirus Affect The Body?
https://www.youtube.com/watch?v=C3TLS6i7Amo

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