More than 1,000 people are expected to march through Bristol city centre on Saturday, says an organiser of an anti-vaccine event.
Angus Lancaster, a member of Stand Up Bristol, says demonstrators will walk through Broadmead, Corn Street and other parts of the city centre on December 12.
The last Stand Up Bristol protest saw around 400 people gather at College Green on November 14, to oppose the second coronavirus lockdown.
Four men and one woman were later charged with offences including participating in a gathering and failing to comply with the directions of police.
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